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Faq: Vitamins To Prevent Cancer, Heart Disease?


A National Task Force That's Been Studying The Issue For 2 Years Says There Is Not Enough Evidence To Show They Help.

 Because the hormone leptin is made by fat tissue, patients with generalized lipodystrophy have very low leptin levels. Leptin regulates food intake and other hormones, such as insulin. Patients with both types of generalized lipodystrophy often develop severe insulin resistance at a young age and may have diabetes mellitus that is difficult to control or very high levels of triglycerides in the blood (hypertriglyceridemia) that can lead to inflammation of the pancreas. ?Myalept is the first approved therapy indicated for treating the complications associated with congenital or acquired generalized lipodystrophy and provides a needed treatment option for patients with this orphan disease,? said Mary Parks, M.D., deputy director of the Office of Drug Evaluation II in the FDA's Center for Drug Evaluation and Research. The safety and effectiveness of Myalept, an analog of leptin made through recombinant DNA technology, were evaluated in an open-label, single-arm study that included 48 patients with congenital or acquired generalized lipodystrophy who also had diabetes mellitus, hypertriglyceridemia, and/or elevated levels of fasting insulin.
FDA Approves Myalept for Rare Metabolic Disease


"i Used To Take Them [to Minuteclinic] All The Time Because My Pediatrician's Office Was A Pain In The Neck," Hoffman Says.


retail Clinics For Kids: No Sub For Pediatricians

Reviewed By Michael W.


 25, 2014 -- Like many busy parents, Ellen Hoffman likes the convenience of the MinuteClinic, a handful of which can be found in CVS pharmacies within a few miles of her home in Bethesda, MD. Her two daughters, 14 and 12, often get ear infections or colds that are going around. "I used to take them [to MinuteClinic] all the time because my pediatrician's office was a pain in the neck," Hoffman says. "I could never get in there." Eventually, though, her local MinuteClinics became so popular that their wait times were as long as those at the pediatrician's office. Still, Hoffman says, she takes her girls to MinuteClinics in Florida when they come down with something while visiting their grandparents. "It's better than not having that resource, but it doesn't replace having your own doctor," Hoffman says. That's the message the American Academy of Pediatrics (AAP) is trying to get through to parents in a new update of its 2006 policy statement about retail-based clinics in pharmacies, supermarkets, and "big box" stores. The group continues to oppose the retail clinics, calling them "an inappropriate source of primary care for pediatric patients." Compared to 2006, "there's a lot more of them, and our patients are using them," says Geoffrey Simon, MD, a pediatrician in Wilmington, DE.
Retail Clinics for Kids: No Sub for Pediatricians

 Reviewed by Michael W. Smith, MD Feb. 24, 2014 -- Scratch vitamins and supplements off your list of things to do to help prevent heart disease and cancer , at least for now. A national task force that's been studying the issue for 2 years says there is not enough evidence to show they help.

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